1,2-Dichlorobenzene → 3,5-Diallyl-4-hydroxybenzoic acid methyl ester

HRID 5929

반응식

HRID 5929 반응식
[CH2:1]([C:4]1[CH:5]=[C:6]([CH:11]=[CH:12][C:13]=1[O:14]CC=C)[C:7]([O:9][CH3:10])=[O:8])[CH:2]=[CH2:3].C(OCC)(=O)C.Cl[C:25]1[CH:30]=CC=C[C:26]=1Cl>CCCCCC>[OH:14][C:13]1[C:12]([CH2:30][CH:25]=[CH2:26])=[CH:11][C:6]([C:7]([O:9][CH3:10])=[O:8])=[CH:5][C:4]=1[CH2:1][CH:2]=[CH2:3]

참가 물질

5

반응물 3

HCID 72391,2-DichlorobenzeneHCID 8857Ethyl AcetateHCID 112417484-Allyloxy-3-allylbenzoic acid methyl ester

생성물 1

HCID 193856193,5-Diallyl-4-hydroxybenzoic acid methyl ester수율 97%

시약·촉매·용매 1

HCID 8058Hexane용매2회

실험 절차

The product of Step A (3.2 g, 13.8 mmol) was refluxed in 1,2-dichlorobenzene for 3 days in the presence of a catalytic amount of BHT (10 mg). Flash column chromatography of the mixture using hexane and then 10% and 20% ethyl acetate in hexane afforded 3.1 g (97%) of the title compound.

출처 및 근거

ORD 기록
ord-3170c5d6164841af935791c864839bf7
출처 데이터셋
uspto-grants-1993_09
특허 번호
US05246944

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