Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Di-para-toluoyl-L-tartaric acid → (-)-(2R,3S)-2-Amino-3-hydroxy-3-pyridin-4-yl-1-pyrrolidin-1-yl-propan-1-one di-p-toluoyl-L-tartrate
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Di-para-toluoyl-L-tartaric acid | HCID 29414711 | — |
| 반응물 | 2-Amino-3-hydroxy-3-pyridin-4-yl-1-pyrrolidin-1-yl-propan-1-one dihydrochloride | HCID 66901564 | — |
| 생성물 | (-)-(2R,3S)-2-Amino-3-hydroxy-3-pyridin-4-yl-1-pyrrolidin-1-yl-propan-1-one di-p-toluoyl-L-tartrate | HCID 131734560 | — |
반응 단계
Resolving the (+/−)-DL-threo-2-amino-3-hydroxy-3-pyridin-4-yl-1-pyrrolidin-1-yl-propan-1-one dihydrochloride in the presence of Di-p-toluoyl-L-tartaric acid to produce (−)-(2R,3S)-2-Amino-3-hydroxy-3-pyridin-4-yl-1-pyrrolidin-1-yl-propan-1-one di-p-toluoyl-L-tartrate;
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US09242935B2 |
| 출처 데이터셋 | uspto-grants-2016_01 |
| ORD ID | ord-eba4f28d77bf40d69acf3a35ce0bb324 |
| 출처 메모 | uspto-grants-2016_01 |