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Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
HRID 593615생성일: 2026년 10월 26일

1-Pyrrolidinesulfonyl chloride → 6-Chloro-2-[5-(pyrrolidine-1-sulfonyloxy)-pyridin-3-yl]-indole-1-carboxylic acid tert-butyl ester

https://huagongshe.com/reaction/593615

반응식

참여 물질

역할이름HCID투입량
반응물1-Pyrrolidinesulfonyl chlorideHCID 6483902—
반응물6-Chloro-2-(5-hydroxy-pyridin-3-yl)-indole-1-carboxylic acid tert-butyl esterHCID 58215545—
생성물6-Chloro-2-[5-(pyrrolidine-1-sulfonyloxy)-pyridin-3-yl]-indole-1-carboxylic acid tert-butyl esterHCID 58215770—

반응 단계

1-Pyrrolidine-sulfonyl chloride and 6-chloro-2-(5-hydroxy-pyridin-3-yl)-indole-1-carboxylic acid tert-butyl ester (Example 160a) are processed according to the method described in Example 160b to give 6-chloro-2-[5-(pyrrolidine-1-sulfonyloxy)-pyridin-3-yl]-indole-1-carboxylic acid tert-butyl ester, which is taken onto the next step without further purification. MS (ESI) m/z 478.1 (M+H)+.

출처 및 근거

DOI10.6084/m9.figshare.5104873.v1
특허 번호US09242963B2
출처 데이터셋uspto-grants-2016_01
ORD IDord-b0284560b9f64148950560c56d05a055
출처 메모uspto-grants-2016_01