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Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
HRID 594085생성일: 2026년 10월 25일

3-bromo-4-(hydroxymethyl)-N-(3-(trifluoromethyl)phenyl)benzamide → 3-bromo-4-formyl-N-(3-(trifluoromethyl)phenyl)benzamide

https://huagongshe.com/reaction/594085

반응식

참여 물질

역할이름HCID투입량
반응물3-bromo-4-(hydroxymethyl)-N-(3-(trifluoromethyl)phenyl)benzamideHCID 90407963—
촉매Manganese dioxideHCID 14801—
용매DichloromethaneHCID 6344—
생성물3-bromo-4-formyl-N-(3-(trifluoromethyl)phenyl)benzamideHCID 90408797100%

반응 단계

MnO2 (8.0 equiv.) was added into a solution of 3-bromo-4-(hydroxymethyl)-N-(3-(trifluoromethyl)phenyl)benzamide (1.0 equiv.) in DCM (0.14 M). The suspension was stirred at rt for 1 hr. The mixture was filtered over celite and concentrated to yield 3-bromo-4-formyl-N-(3-(trifluoromethyl)phenyl)benzamide in 100% yield. LC/MS (m/z)=373.9 (MH+), Rt=0.0.94 min.

출처 및 근거

DOI10.6084/m9.figshare.5104873.v1
특허 번호US09242969B2
출처 데이터셋uspto-grants-2016_01
ORD IDord-4e48c0fa86af45f8b79503bd0b7583b0
출처 메모uspto-grants-2016_01