Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
2-tert-Butyl-1,1,3,3-tetramethylguanidine → 4-((3,5-dimethylisoxazol-4-yl)-methoxy)-N-isobutyl-N-(5-isopropylpyridin-2-yl)benzenesulfonamide
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 2-tert-Butyl-1,1,3,3-tetramethylguanidine | HCID 3571581 | — |
| 반응물 | 4-((3,5-dimethylisoxazol-4-yl)methoxy)-N-(5-isopropylpyridin-2-yl)benzenesulfonamide | HCID 89876015 | — |
| 용매 | Acetonitrile | HCID 6342 | — |
| 생성물 | 4-((3,5-dimethylisoxazol-4-yl)-methoxy)-N-isobutyl-N-(5-isopropylpyridin-2-yl)benzenesulfonamide | HCID 71768627 | 17.1% |
반응 단계
The title compound (7.6 mg) was prepared from 4-((3,5-dimethylisoxazol-4-yl)methoxy)-N-(5-isopropylpyridin-2-yl)benzenesulfonamide (39 mg, 0.097 mmol) and 2-(tert-butyl)-1,1,3,3-tetramethylguanidine (0.020 mL, 0.097 mmol) in acetonitrile (2 mL), following the procedure described for Example 1. LCMS (2 min, formic) Rt 1.37 min, m/z (ES+) 458 (M+H).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US09242972B2 |
| 출처 데이터셋 | uspto-grants-2016_01 |
| ORD ID | ord-3ed7b01455ab436cb4ec550d6e4d9c08 |
| 출처 메모 | uspto-grants-2016_01 |