Lithium borohydride → (S)-2-(2-aminophenyl)-7-methoxy-8-(3-(((S)-7-methoxy-2-(4-methoxyphenyl)-5-oxo-5,11a-dihydro-pyrrolo[2,1-c][1,4]benzodiazepin-8-yl)oxy)propoxy)-pyrrolo[2,1-c][1,4]benzodiazepin-5(11aH)-one
반응식
[Li+].[B-](CC)(CC)CC.[NH2:9][C:10]1[CH:15]=[CH:14][CH:13]=[CH:12][C:11]=1[C:16]1[CH2:17][C@@H:18]2[N:24]([CH:25]=1)[C:23](=[O:26])[C:22]1[CH:27]=[C:28]([O:70][CH3:71])[C:29]([O:31][CH2:32][CH2:33][CH2:34][O:35][C:36]3[C:67]([O:68][CH3:69])=[CH:66][C:39]4[C:40](=[O:65])[N:41]5[CH:56]=[C:55]([C:57]6[CH:62]=[CH:61][C:60]([O:63][CH3:64])=[CH:59][CH:58]=6)[CH2:54][C@H:42]5[C:43](=O)[N:44](COCC[Si](C)(C)C)[C:38]=4[CH:37]=3)=[CH:30][C:21]=1[N:20](COCC[Si](C)(C)C)[C:19]2=O.[BH4-].[Li+]>O1CCCC1>[NH2:9][C:10]1[CH:15]=[CH:14][CH:13]=[CH:12][C:11]=1[C:16]1[CH2:17][C@@H:18]2[N:24]([CH:25]=1)[C:23](=[O:26])[C:22]1[CH:27]=[C:28]([O:70][CH3:71])[C:29]([O:31][CH2:32][CH2:33][CH2:34][O:35][C:36]3[C:67]([O:68][CH3:69])=[CH:66][C:39]4[C:40](=[O:65])[N:41]5[CH:56]=[C:55]([C:57]6[CH:58]=[CH:59][C:60]([O:63][CH3:64])=[CH:61][CH:62]=6)[CH2:54][C@H:42]5[CH:43]=[N:44][C:38]=4[CH:37]=3)=[CH:30][C:21]=1[N:20]=[CH:19]2참가 물질
5
반응물 3
HCID 4148881Lithium borohydride
HCID 23712863Lithium triethylborohydride
HCID 86676192(S)-2-(2-aminophenyl)-7-methoxy-8-(3-(((S)-7-methoxy-2-(4-methoxyphenyl)-5,11-dioxo-10((2-(trimethylsilyl)ethoxy)methyl)-5,10,11,11a-tetrahydro-pyrrolo[2,1-c][1,4]benzodiazepin-8-yl)oxy)propoxy)-10-((2-(trimethylsilyl)ethoxy)methyl)-pyrrolo[2,1-c][1,4]-benzodiazepine-5,11(10H,11aH)-dione생성물 1
