Benzene, 1-ethoxy-2-iodo- → HCID 69082481, 화합물

HRID 594369

반응식

HRID 594369 반응식
C(S([N:7]=[CH:8][CH2:9][CH2:10][C:11]([O:13]C)=O)=O)(C)(C)C.[CH2:15]([O:17][C:18]1[CH:23]=[CH:22][CH:21]=[CH:20][C:19]=1I)[CH3:16].NC(C1C(OC)=CC=CC=1OC)CCC(OC)=O.COC1C=CC=C(OC)C=1C1NC(=O)CC1>>[CH2:15]([O:17][C:18]1[CH:23]=[CH:22][CH:21]=[CH:20][C:19]=1[CH:8]1[NH:7][C:11](=[O:13])[CH2:10][CH2:9]1)[CH3:16]

참가 물질

5

반응물 4

HCID 136415Benzene, 1-ethoxy-2-iodo-HCID 69080911HCID 69080911, 화합물HCID 69082397Methyl 4-amino-4-(2,6-dimethoxyphenyl)butanoateHCID 86695623Methyl 4-((tert-butylsulfinyl)imino)butanoate

생성물 1

HCID 69082481HCID 69082481, 화합물

실험 절차

Synthesized from methyl 4-((tert-butylsulfinyl)imino)butanoate and commercially available 1-ethoxy-2-iodobenzene according to the procedures described for the preparations of methyl 4-amino-4-(2,6-dimethoxyphenyl)butanoate and 5-(2,6-dimethoxyphenyl)pyrrolidin-2-one. The target product 5-(2-ethoxyphenyl)pyrrolidin-2-one was obtained as a colorless solid after purification by FC (heptane/AcOEt=7/3 to 3/7). LC-MS (conditions D): tR=0.81 min.; [M+H]+: 205.99 g/mol.

출처 및 근거

ORD 기록
ord-38ce28f7d58443a1b399ce79b538f257
출처 데이터셋
uspto-grants-2016_01
특허 번호
US09242970B2

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