Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
2,6-Dimethoxybenzaldehyde → 6-(2,6-dimethoxyphenyl)-1-((1-methyl-1H-indol-5-yl)methyl)piperidin-2-one
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 2,6-Dimethoxybenzaldehyde | HCID 96404 | — |
| 반응물 | (1-methyl-1H-indol-5-yl)methylamine | HCID 18525752 | — |
| 생성물 | 6-(2,6-dimethoxyphenyl)-1-((1-methyl-1H-indol-5-yl)methyl)piperidin-2-one | HCID 69085388 | — |
반응 단계
Prepared according to the described general procedure 6 (GP6) with commercially available (1-methyl-1H-indol-5-yl)methanamine and commercially available 2,6-dimethoxybenzaldehyde. Subsequent purification by preparative HPLC afforded the target compound. LC-MS (conditions E): tR=0.76 min.; [M+H]+: 379.12 g/mol.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US09242970B2 |
| 출처 데이터셋 | uspto-grants-2016_01 |
| ORD ID | ord-1af8e1f89f8145c9b2340777f6dfc956 |
| 출처 메모 | uspto-grants-2016_01 |