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Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
HRID 594707생성일: 2026년 10월 27일

3-Ethoxybenzaldehyde → 5-(2-Ethoxy-6-fluorophenyl)-1-(3-ethoxybenzyl)-3-methylpyrrolidin-2-one

https://huagongshe.com/reaction/594707

반응식

참여 물질

역할이름HCID투입량
반응물3-EthoxybenzaldehydeHCID 89908—
반응물Ethyl 4-amino-4-(2-ethoxy-6-fluorophenyl)-2-methylbutanoateHCID 69083532—
생성물5-(2-Ethoxy-6-fluorophenyl)-1-(3-ethoxybenzyl)-3-methylpyrrolidin-2-oneHCID 69084515—

반응 단계

Prepared according to the described general procedure 2 (GP2) by reaction of ethyl 4-amino-4-(2-ethoxy-6-fluorophenyl)-2-methylbutanoate with commercially available 3-ethoxybenzaldehyde. Subsequent purification by preparative HPLC afforded the target compound. LC-MS (conditions A): tR=0.92 min.; [M+H]+: 372.03 g/mol.

출처 및 근거

DOI10.6084/m9.figshare.5104873.v1
특허 번호US09242970B2
출처 데이터셋uspto-grants-2016_01
ORD IDord-8fa82841ee294f60b7591a6be06b96a0
출처 메모uspto-grants-2016_01