5-Fluoro-1-methyl-1H-indole-2-carbaldehyde → HCID 69082472, 화합물
반응식
[NH2:1][CH:2]([C:11]1[C:16]([O:17][CH3:18])=[CH:15][CH:14]=[CH:13][C:12]=1[O:19][CH3:20])[CH2:3][CH:4]([CH3:10])[C:5]([O:7]CC)=O.[F:21][C:22]1[CH:23]=[C:24]2[C:28](=[CH:29][CH:30]=1)[N:27]([CH3:31])[C:26]([CH:32]=O)=[CH:25]2>>[CH3:18][O:17][C:16]1[CH:15]=[CH:14][CH:13]=[C:12]([O:19][CH3:20])[C:11]=1[CH:2]1[N:1]([CH2:32][C:26]2[N:27]([CH3:31])[C:28]3[C:24]([CH:25]=2)=[CH:23][C:22]([F:21])=[CH:30][CH:29]=3)[C:5](=[O:7])[CH:4]([CH3:10])[CH2:3]1참가 물질
3
실험 절차
Prepared according to the described general procedure 2 (GP2) by reaction of ethyl 4-amino-4-(2,6-dimethoxyphenyl)-2-methylbutanoate with commercially available 5-fluoro-1-methyl-1H-indole-2-carbaldehyde. Subsequent purification by preparative HPLC afforded the target compound. LC-MS (conditions A): tR=0.90 min.; [M+H]+: 397.08 g/mol.
후처리
- customPrepared
- customSubsequent purification by preparative HPLC
- customafforded the target compound