Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
1-methyl-1H-indole-5-carbaldehyde → 5-(2,6-dimethoxyphenyl)-3-methyl-1-((1-methyl-1H-indol-5-yl)methyl)pyrrolidin-2-one
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 1-methyl-1H-indole-5-carbaldehyde | HCID 7537534 | — |
| 반응물 | Ethyl 4-amino-4-(2,6-dimethoxyphenyl)-2-methylbutanoate | HCID 69085588 | — |
| 생성물 | 5-(2,6-dimethoxyphenyl)-3-methyl-1-((1-methyl-1H-indol-5-yl)methyl)pyrrolidin-2-one | HCID 69084514 | — |
반응 단계
Prepared according to the described general procedure 2 (GP2) by reaction of ethyl 4-amino-4-(2,6-dimethoxyphenyl)-2-methylbutanoate with commercially available 1-methyl-1H-indole-5-carbaldehyde. Subsequent purification by preparative HPLC afforded the target compound. LC-MS (conditions A): tR=0.84 min.; [M+H]+: 378.93 g/mol.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US09242970B2 |
| 출처 데이터셋 | uspto-grants-2016_01 |
| ORD ID | ord-afd129c27ea94903b2d9002c22c5399c |
| 출처 메모 | uspto-grants-2016_01 |