Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Aminoethyl sulfate → 2-(2-Hydroxy-4-phenylbutyl)aminoethyl hydrogen sulphate
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Aminoethyl sulfate | HCID 70223 | — |
| 반응물 | 2-(2-Phenylethyl)oxirane | HCID 135955 | — |
| 용매 | Methanol | HCID 887 | — |
| 용매 | Sodium Hydroxide | HCID 14798 | — |
| 생성물 | 2-(2-Hydroxy-4-phenylbutyl)aminoethyl hydrogen sulphate | HCID 20354781 | — |
반응 단계
A mixture of 1,2-epoxy-4-phenylbutane (1.48 g.) and 2-aminoethyl hydrogen sulphate (7.05 g.) in methanol (7.5 ml.) and sodium hydroxide solution (18N, 2.8 ml.) is stirred at ambient temperature for 2 hours. The 2-(2-hydroxy-4-phenylbutyl)aminoethyl hydrogen sulphate formed as intermediate is not isolated but is cyclised in situ as follows:
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04010266 |
| 출처 데이터셋 | uspto-grants-1977_03 |
| ORD ID | ord-241d6d8f0f204c859c915f205a38dc50 |
| 출처 메모 | uspto-grants-1977_03 |