Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
2-Hydroxyacetohydrazide → HCID 21450833, 화합물
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 2-Hydroxyacetohydrazide | HCID 350536 | — |
| 반응물 | 5-(2-fluorophenyl)-7-nitro-3H-1,4-benzodiazepine-2(1H)-thione | HCID 12371434 | — |
| 용매 | 1-Butanol | HCID 263 | — |
| 생성물 | HCID 21450833 | HCID 21450833 | — |
반응 단계
In the manner given in Preparation 1, a solution of 1,3-dihydro-7-nitro-5-(o-fluorophenyl)-2H-1,4-benzodiazepine-2-thione in n-butyl alcohol is heated to reflux with hydroxyacetic acid hydrazide to give 8-nitro-1-(hydroxymethyl)-6-(o-fluorophenyl)-4H-s-triazolo[4,3-a][1,4]benzodiazepine. Preparation 4 8-(Trifluoromethyl)-1-(hydroxymethyl)-6-(o-chlorophenyl)-4H-s-triazolo[4,3-a][1,4]benzodiazepine
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04010177 |
| 출처 데이터셋 | uspto-grants-1977_03 |
| ORD ID | ord-713044aba8ad421e9e09ffbb5fc874dd |
| 출처 메모 | uspto-grants-1977_03 |