Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Chloroacetyl chloride → 1H-1,4-Benzodiazepine
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Chloroacetyl chloride | HCID 6577 | — |
| 반응물 | Sodium Acetate | HCID 517045 | — |
| 반응물 | HCID 20291823 | HCID 20291823 | — |
| 생성물 | 1H-1,4-Benzodiazepine | HCID 148431 | — |
반응 단계
In the manner given in Preparation 10, 7-chloro-5(2,6-difluorophenyl)-3H-1,4-benzodiazepin-2-yl hydrazine is reacted with chloroacetyl chloride and after 1.5 hours with sodium acetate, then the mixture is refluxed to give 8-chloro-1-(chloromethyl)-6-(2,6-difluorophenyl)-4H-s-triazolo[4,3-a][1,4-benzodiazepine. Preparation 14 8-Nitro-1-(bromomethyl)-6-(o-chlorophenyl)-4H-s-triazolo[4,3-a][1,4]benzodiazepine
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04010177 |
| 출처 데이터셋 | uspto-grants-1977_03 |
| ORD ID | ord-e1ceb363288a48ba9780f4b7d7d00abc |
| 출처 메모 | uspto-grants-1977_03 |