참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|
| 반응물 | Styrene Oxide | HCID 7276 | — |
| 반응물 | (+-)-3,4-Dimethoxyamphetamine | HCID 8423 | — |
| 용매 | Benzene | HCID 241 | — |
| 생성물 | N-[2-(3,4-dimethoxyphenyl)-1-methylethyl]-2-hydroxy-2-phenylethylamine | HCID 11347606 | — |
반응 단계
A mixture of 20 g. (0.102 mol) of 1-(3,4-dimethoxyphenyl)-2-aminopropane and 12.01 ml. (0.102 mol) of styrene oxide is heated and stirred at 100° C. under argon for 18 hours. The cooled reaction mixture is dissolved in a minimum amount of benzene and petroleum ether is then added to precipitate a solid which turned to a liquid upon standing. Fractional vacuum distillation yields N-[2-(3,4-dimethoxyphenyl)-1-methylethyl]-2-hydroxy-2-phenylethylamine, b.p. 205°-225° C./0.2 mm.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| 특허 번호 | US04011319 |
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| 출처 데이터셋 | uspto-grants-1977_03 |
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| ORD ID | ord-b713955d61084a38a3d57eaa2081338a |
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| 출처 메모 | uspto-grants-1977_03 |
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