Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Water → 5-(3,7,11,15-Tetramethylhexadecyloxy)-2-furoic acid
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Water | HCID 962 | — |
| 반응물 | Sodium hydride | HCID 24758 | — |
| 반응물 | Dihydrophytol | HCID 102459 | — |
| 반응물 | 5-Chlorofuran-2-carboxylic acid | HCID 234853 | — |
| 용매 | Toluene | HCID 1140 | — |
| 생성물 | 5-(3,7,11,15-Tetramethylhexadecyloxy)-2-furoic acid | HCID 21450431 | — |
반응 단계
A mixture of 59.8 g (0.2 mole) of 3,7,11,15-tetramethyl-1-hexadecanol and 19.2 g (0.4 mole) of sodium hydride (50% in oil) in 1 liter of toluene is refluxed with stirring for 2 hours then cooled to room temperature. To the mixture 29.3 g (0.2 mole) of 5-chloro-2-furoic acid is added and the mixture is refluxed with stirring for 24 hours. Upon cooling to room temperature the mixture is acidified with glacialacetic acid and water is added. The toluene layer is evaporated and allowed to crystallize to give 5-(3,7,11,15-tetramethylhexadecyloxy)-2-furoic acid.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04011334 |
| 출처 데이터셋 | uspto-grants-1977_03 |
| ORD ID | ord-fd13263df78048ae968f86bbe42ce2d6 |
| 출처 메모 | uspto-grants-1977_03 |