Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Phosphorus oxychloride → 3-Chlorocinnamonitrile
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Phosphorus oxychloride | HCID 24813 | — |
| 반응물 | Sodium Pyrosulfite | HCID 656671 | — |
| 반응물 | 3-(3-Chlorophenyl)prop-2-enamide | HCID 53439624 | — |
| 생성물 | 3-Chlorocinnamonitrile | HCID 367316 | 59.5% |
반응 단계
m-Chlorocinnamamide (1.39 g.) was mixed with sodium metabisulphite (0.72 g.) and phosphoryl chloride (3 ml.). The mixture was heated on the steam-bath for 2.5 hr. and the phosphoryl chloride removed under reduced pressure. The residue was washed well with water, leaving slightly impure m-chlorocinnamonitrile (0.744 g., 59.5%). Recrystallisation from aqueous acetone gave m-chlorocinnamonitrile, m.p. 56°-57°, λmax. (EtOH) 226, 270 nm. ε 19000, 22500.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04012377 |
| 출처 데이터셋 | uspto-grants-1977_03 |
| ORD ID | ord-f89108d6e9ad4052b1035597098795e2 |
| 출처 메모 | uspto-grants-1977_03 |