Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Water → 2-Propenenitrile, 3-(4-fluorophenyl)-
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Water | HCID 962 | — |
| 반응물 | Hydroxyamine hydrochloride | HCID 443297 | — |
| 반응물 | Sodium Formate | HCID 2723810 | — |
| 반응물 | 3-(4-Fluorophenyl)-2-propenal | HCID 53384379 | — |
| 용매 | Formic Acid | HCID 284 | — |
| 생성물 | 2-Propenenitrile, 3-(4-fluorophenyl)- | HCID 367324 | 70.4% |
반응 단계
p-Fluorocinnamaldehyde (9.0 g.) was refluxed for 1 hr. in 98% formic acid containing sodium formate (10 g.) and hydroxylamine hydrochloride (7 g.). The solution was cooled and poured into water (275 ml.), giving a solid. This was washed well with water, leaving p-fluorocinnamonitrile (6.21 g., 70%), m.p. 64°-65°, λmax. (EtOH) 271 nm ε 22500.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04012377 |
| 출처 데이터셋 | uspto-grants-1977_03 |
| ORD ID | ord-e9949bbebf3b423f8e3963e521514c62 |
| 출처 메모 | uspto-grants-1977_03 |