5-[p-(1-Cyclooctenyl)-phenoxy]-pentanoic acid ethyl ester → 5-(p-Cyclooctyl-phenoxy)-pentanoic acid ethyl ester

HRID 597306

반응식

HRID 597306 반응식
[CH2:1]([O:3][C:4](=[O:24])[CH2:5][CH2:6][CH2:7][CH2:8][O:9][C:10]1[CH:15]=[CH:14][C:13]([C:16]2[CH2:23][CH2:22][CH2:21][CH2:20][CH2:19][CH2:18][CH:17]=2)=[CH:12][CH:11]=1)[CH3:2].[H][H]>[Pd].C(O)C>[CH2:1]([O:3][C:4](=[O:24])[CH2:5][CH2:6][CH2:7][CH2:8][O:9][C:10]1[CH:15]=[CH:14][C:13]([CH:16]2[CH2:23][CH2:22][CH2:21][CH2:20][CH2:19][CH2:18][CH2:17]2)=[CH:12][CH:11]=1)[CH3:2]

참가 물질

5

반응물 2

HCID 543745795-[p-(1-Cyclooctenyl)-phenoxy]-pentanoic acid ethyl esterHCID 178418361HCID 178418361, 화합물

생성물 1

HCID 543712055-(p-Cyclooctyl-phenoxy)-pentanoic acid ethyl ester

시약·촉매·용매 2

HCID 23938Palladium촉매HCID 702Ethanol용매

실험 절차

2 g of palladium on charcoal (5% strength) are added to a solution of 20 g of 5-[p-(1-cyclooctenyl)-phenoxy]-pentanoic acid ethyl ester in 100 ml of ethanol and hydrogenation is carried out at room temperature and normal pressure until one equivalent of hydrogen has been absorbed. The catalyst is then filtered off and the filtrate is evaporated to dryness in vacuo. Distillation of the evaporation residue in a high vacuum gives 5-(p-cyclooctyl-phenoxy)-pentanoic acid ethyl ester of boiling point 170° -175° C at 0.05 mm Hg.

후처리

  1. customis carried out at room temperature
  2. filtrationThe catalyst is then filtered off
  3. customthe filtrate is evaporated to dryness in vacuo
  4. distillationDistillation of the evaporation residue in a high vacuum

출처 및 근거

ORD 기록
ord-f98040b25c974e0393e288e063af74d1
출처 데이터셋
uspto-grants-1977_03
특허 번호
US04013708

연결된 노트

불러오는 중…