Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Methyl iodide → N-(2,6-dichlorobenzoyl)-N-(methoxymethyl)-N'-(4-chlorophenyl)-urea
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Methyl iodide | HCID 6328 | — |
| 반응물 | Chloromethyl Methyl Ether | HCID 7864 | — |
| 반응물 | Potassium Hydroxide | HCID 14797 | — |
| 반응물 | 2,6-dichloro-N-(((4-chlorophenyl)amino)carbonyl)benzamide | HCID 92300 | — |
| 용매 | Dimethylformamide | HCID 6228 | — |
| 생성물 | N-(2,6-dichlorobenzoyl)-N-(methoxymethyl)-N'-(4-chlorophenyl)-urea | HCID 19006383 | — |
반응 단계
10.3 g of N-(2,6-dichlorobenzoyl)-N'-(4-chlorophenyl)-urea and 1.88 g of powdered potassium hydroxide (90%) are dissolved 40 ml of dimethyl formamide, after which 4.7 g of methyl iodide are added drop by drop to the clear solution. The resulting reaction is exothermic. After stirring for two hours the solution is diluted with ice water and the solid substance is isolated. Yield 10.3 g. Melting point 124°-126° C. In a completely similar manner but using methoxymethylchloride instead of methyliodide, N-(2,6-dichlorobenzoyl)-N-(methoxymethyl)-N'-(4-chlorophenyl)-urea is produced. Melting point 121.5°-122.5° C.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04013717 |
| 출처 데이터셋 | uspto-grants-1977_03 |
| ORD ID | ord-90a2957f86b047e0905f53236d6136b7 |
| 출처 메모 | uspto-grants-1977_03 |