Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Water → 3-Oxo-17beta(1oxopropoxy)androst-4en-19-al
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Water | HCID 962 | — |
| 반응물 | 19-Hydroxy-17beta(1-oxopropoxy)androst-4-en-3-one | HCID 54223287 | — |
| 반응물 | Jones' reagent | HCID 131709961 | — |
| 용매 | Acetone | HCID 180 | — |
| 생성물 | 3-Oxo-17beta(1oxopropoxy)androst-4en-19-al | HCID 86734575 | — |
반응 단계
To a solution of 14 g of 19-hydroxy-17β-(1-oxopropoxy)androst-4-en-3-one in 1 liter of acetone cooled in an ice bath is added 13.3 ml of Jones reagent over 1 hour after which the reaction mixture is poured into a large volume of water and extracted with ether. The ether extract is dried over magnesium sulfate, filtered and the solvent removed. The residue is crystallized from acetone-hexane to give 3-oxo-17β(1-oxopropoxy)-androst-4-en-19-al, M.P. 119°-121° C.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04013762 |
| 출처 데이터셋 | uspto-grants-1977_03 |
| ORD ID | ord-351a1df61290434e83384db44ff64283 |
| 출처 메모 | uspto-grants-1977_03 |