Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Potassium Carbonate → HCID 178509280, 화합물
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Potassium Carbonate | HCID 11430 | — |
| 반응물 | Hydrazine hydrate (1:1) | HCID 24654 | — |
| 반응물 | N-(2-((4-chlorophenethyl)(piperidin-4-yl)amino)ethyl)benzamide | HCID 121410331 | — |
| 반응물 | N-cyanopiperazine-1-carbimidothioate | HCID 131737066 | — |
| 생성물 | HCID 178509280 | HCID 178509280 | — |
반응 단계
N-(2-((4-Chlorophenethyl)(piperidin-4-yl)amino)ethyl)benzamide obtained in Step 4 was reacted with K2CO3 and S,S′-dimethyl-N-cyano-dithioiminocarbonate, followed by the cyclization of the intermediate (N-cyanopiperazine-1-carbimidothioate) with hydrazine monohydrate in a manner described in Procedure 3. Purification over silica gel provided pure product.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US09440953B2 |
| 출처 데이터셋 | uspto-grants-2016_09 |
| ORD ID | ord-74267245d16542a2bcfaf4369e448bf8 |
| 출처 메모 | uspto-grants-2016_09 |