p-Tolylacetonitrile → HCID 73053000, 화합물

HRID 59827

반응식

[F:1][C:2]1[CH:7]=[CH:6][C:5]([N:8]2[C:12]([C:13]3[CH:18]=[CH:17][C:16]([N+:19]([O-:21])=O)=[CH:15][CH:14]=3)=[CH:11][CH:10]=[N:9]2)=[CH:4][CH:3]=1.[C:22]1([CH3:31])[CH:27]=[CH:26][C:25]([CH2:28]C#N)=[CH:24][CH:23]=1>>[F:1][C:2]1[CH:3]=[CH:4][C:5]([N:8]2[C:12]([C:13]3[CH:14]=[CH:15][C:16]4=[N:19][O:21][C:31]([C:22]5[CH:27]=[CH:26][C:25]([CH3:28])=[CH:24][CH:23]=5)=[C:17]4[CH:18]=3)=[CH:11][CH:10]=[N:9]2)=[CH:6][CH:7]=1

참가 물질

반응물 2

HCID 76280p-Tolylacetonitrile

HCID 900333991-(4-fluoro-phenyl)-5-(4-nitro-phenyl)-1H-pyrazole2회

생성물 1

HCID 73053000HCID 73053000, 화합물

실험 절차

The title compound, yellow solid (28 mg, 22%), MS (ISP) m/z=370.2 [(M+H)+], mp 158° C., was prepared in accordance with the general method of example 1 from 1-(4-fluoro-phenyl)-5-(4-nitro-phenyl)-1H-pyrazole (intermediate C) (100 mg, 353 μmol) and commercially available 2-(p-tolyl)-acetonitrile.

출처 및 근거

ORD 기록: ord-eebf42f89adb473d8d2eca1dd8e977fd
출처 데이터셋: uspto-grants-2016_09
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US09440962B2

연결된 노트

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