Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Hydrochloric Acid → (6-Chloro-benzooxazol-2-yl)-(R)-pyrrolidin-3-yl-amine, hydrochloride
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Hydrochloric Acid | HCID 313 | — |
| 반응물 | 2,6-Dichlorobenzoxazole | HCID 77175 | — |
| 반응물 | (6-Chloro-benzooxazol-2-yl)-pyrrolidin-3-yl-amine | HCID 57748894 | — |
| 생성물 | (6-Chloro-benzooxazol-2-yl)-(R)-pyrrolidin-3-yl-amine, hydrochloride | HCID 131728720 | — |
반응 단계
In analogy to the procedure described for the synthesis of (6-Chloro-benzooxazol-2-yl)-pyrrolidin-3-yl-amine; hydrochloride (example 1, step 1) the title compound was prepared from 2,6-dichloro-benzoxazole (commercially available) and R-3-amino-pyrrolidine-1-carboxylic acid tert-butyl ester (commercially available) and subsequent cleavage of the tert-butyl oxy carbonyl protecting group under acidic conditions. (MH+) 238.0.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07897627B2 |
| 출처 데이터셋 | uspto-grants-2011_03 |
| ORD ID | ord-4269e0b778fa46ffacdf267cba5921d7 |
| 출처 메모 | uspto-grants-2011_03 |