HCID 59379802, 화합물 → HCID 59379814, 화합물

HRID 598748노트

반응식

HRID 598748 반응식
[CH3:1][O:2][C:3](=[O:25])[C:4]([C:6]1[C:15]2[C:10](=[CH:11][CH:12]=[CH:13][CH:14]=2)[C:9]([O:16][CH2:17][CH2:18][N:19]2[CH2:24][CH2:23][O:22][CH2:21][CH2:20]2)=[CH:8][CH:7]=1)=[O:5]>CO.[Pd]>[CH3:1][O:2][C:3](=[O:25])[CH:4]([OH:5])[C:6]1[C:15]2[C:10](=[CH:11][CH:12]=[CH:13][CH:14]=2)[C:9]([O:16][CH2:17][CH2:18][N:19]2[CH2:20][CH2:21][O:22][CH2:23][CH2:24]2)=[CH:8][CH:7]=1

참가 물질

4

반응물 1

HCID 59379802HCID 59379802, 화합물

생성물 1

HCID 59379814HCID 59379814, 화합물

시약·촉매·용매 2

HCID 887Methanol용매HCID 23938Palladium용매

실험 절차

To a solution of 12 (1 g, 2.9 mmol) in MeOH (10 mL), Pd/C (10 wt %) was added and the mixture stirred at rt under H2 atmosphere. Upon completion of the reaction (monitored by LCMS), the mixture was filtered through celite and the filtrate evaporated to give a yellow oil which solidified upon standing. Calculated mass=345. Observed mass=345.

후처리

  1. customUpon completion of the reaction (monitored by LCMS)
  2. filtrationthe mixture was filtered through celite
  3. customthe filtrate evaporated
  4. customto give a yellow oil which

출처 및 근거

ORD 기록
ord-4a4637a108dd4243855c9e7ec6d2251d
출처 데이터셋
uspto-grants-2011_03
특허 번호
US07897599B2

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