Arnebin I → Shikonin

HRID 598801

반응식

HRID 598801 반응식
[CH3:1][C:2]([CH3:27])=[CH:3][CH2:4][CH:5]([O:20]C(C=C(C)C)=O)[C:6]1[C:16](=[O:17])[C:15]2[C:10](=[C:11]([OH:19])[CH:12]=[CH:13][C:14]=2[OH:18])[C:8](=[O:9])[CH:7]=1.CC(C)=CC[C@@H](OC(C)=O)C1C(=O)C2C(O)=CC=C(O)C=2C(=O)C=1>>[CH3:1][C:2]([CH3:27])=[CH:3][CH2:4][C@@H:5]([OH:20])[C:6]1[C:16](=[O:17])[C:15]2[C:14]([OH:18])=[CH:13][CH:12]=[C:11]([OH:19])[C:10]=2[C:8](=[O:9])[CH:7]=1

참가 물질

3

반응물 2

HCID 32465Arnebin IHCID 479501Acetylshikonin

생성물 1

HCID 479503Shikonin

실험 절차

Weigh 5.0 mg of shikonin, β,β-dimethylacrylshikonin, acetylshikonin obtained in Preparation example 1 or Preparation example 2, respectively. Dissolve the compounds in 1 ml DMSO. After diluting by 50 times with RPMI-1640 culture medium, pack them separately and further dilute into the following concentration: 100, 50, 25, 12.5, 6.25, 3.13, 1.56, 0.78, 0.39 (μg/ml).

출처 및 근거

ORD 기록
ord-03ff5af5a2a847fab6aba0b1babc4193
출처 데이터셋
uspto-grants-2011_03
특허 번호
US07897640B2

연결된 노트

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