Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
2-Aminothiazole → 1-(4-Chlorophenoxy)-2-nitrobenzene
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 2-Aminothiazole | HCID 2155 | — |
| 반응물 | 4-Chlorophenol | HCID 4684 | — |
| 반응물 | 1-Fluoro-2-nitrobenzene | HCID 73895 | — |
| 반응물 | 2-(4-Chlorophenoxy)aniline | HCID 76010 | — |
| 생성물 | 1-(4-Chlorophenoxy)-2-nitrobenzene | HCID 3016050 | 71% |
| 생성물 | N-[2-(4-Chlorophenoxy)phenyl]-N'-(thiazol-2-yl)urea | HCID 59732782 | 62% |
반응 단계
2-(4-Chlorophenoxy)-1-nitrobenzene (0.88 g, 71%) was prepared from 4-chlorophenol (0.70 g, 5.5 mmol) and 1-fluoro-2-nitrobenzene (0.71 g, 5.0 mmol) following the general procedure A. This was reduced to 2-(4-chlorophenoxy)aniline (0.50 g, 65%) following general procedure B. N-[2-(4-Chlorophenoxy)phenyl]-N′-(thiazol-2-yl)urea (106 mg, 62%) was prepared from 2-(4-chlorophenoxy)aniline (109 mg, 0.5 mmol) and 2-aminothiazole (60 mg, 0.6 mmol) following the general procedure D.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07897628B2 |
| 출처 데이터셋 | uspto-grants-2011_03 |
| ORD ID | ord-e82e4c952c1d47f8bb2ab02b7706726a |
| 출처 메모 | uspto-grants-2011_03 |