Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
2-Aminothiazole → 3-Cyclopentylmethoxy-4-nitrotoluene
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 2-Aminothiazole | HCID 2155 | — |
| 반응물 | Benzene, 2-fluoro-4-methyl-1-nitro- | HCID 67966 | — |
| 반응물 | Cyclopentanemethanol | HCID 77195 | — |
| 반응물 | 2-(Cyclopentylmethoxy)-4-methylaniline | HCID 26189518 | — |
| 생성물 | 1-(2-Cyclopentylmethoxy-4-methyl-phenyl)-3-thiazol-2-yl-urea | HCID 59732830 | 68% |
| 생성물 | 3-Cyclopentylmethoxy-4-nitrotoluene | HCID 66998981 | 70% |
반응 단계
3-Cyclopentylmethoxy-4-nitrotoluene (0.82 g, 70%) was prepared from cyclopentylmethanol and 3-fluoro-4-nitrotoluene (0.77 g, 5.0 mmol) following the general procedure G. This was reduced to 2-cyclopentylmethoxy-4-methyl-aniline (0.58 g, 81%) following general procedure C. 1-(2-Cyclopentylmethoxy-4-methyl-phenyl)-3-thiazol-2-yl-urea (225 mg, 68%) was prepared from 2-cyclopentylmethoxy-4-methyl-aniline (205 mg, 1.0 mmol) and 2-aminothiazole (100 mg, 1.0 mmol) following the general procedure D.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07897628B2 |
| 출처 데이터셋 | uspto-grants-2011_03 |
| ORD ID | ord-4d23c0c9c7c44b9d8c759c8de255bb33 |
| 출처 메모 | uspto-grants-2011_03 |