Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Ammonia → Benzo[c][1,2,5]thiadiazole-5-carboxylic acid (4r)-(1-azatricyclo[3.3.1.13,7]dec-4-yl)-amide hydrochloride
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Ammonia | HCID 222 | — |
| 반응물 | 2,1,3-Benzothiadiazole-5-carboxylic acid | HCID 602011 | — |
| 반응물 | 1-Azatricyclo[3.3.1.1,3,7]decan-4-amine hydrochloride | HCID 67152122 | — |
| 생성물 | Benzo[c][1,2,5]thiadiazole-5-carboxylic acid (4r)-(1-azatricyclo[3.3.1.13,7]dec-4-yl)-amide hydrochloride | HCID 67152115 | — |
반응 단계
Prepared from (4r)-1-azatricyclo[3.3.1.13,7]dec-4-ylamine hydrochloride and benzo[c][1,2,5]thiadiazole-5-carboxylic acid according to methods A and C. 1H NMR (300 MHz, methanol-d4) δ ppm 2.08-2.34 (m, 5H), 2.51 (s, 2H), 3.42-3.64 (m, 4H), 3.88 (d, J=12.5 Hz, 2H), 4.33 (s, 1H), 7.90-8.51 (m, 1H), 8.98 (s, 1H), 9.57 (s, 1H). MS (DCI/NH3) m/z 315. Anal. Calculated for C16H18N4OS.HCl: C, 54.77; H, 5.46; N, 15.97. Found: C, 53.82; H, 5.31; N, 16.17.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07897766B2 |
| 출처 데이터셋 | uspto-grants-2011_03 |
| ORD ID | ord-72417948ba394953a53b3f847d5a7f86 |
| 출처 메모 | uspto-grants-2011_03 |