Ammonia → HCID 67152204, 화합물

HRID 599252노트

반응식

HRID 599252 반응식
[ClH:1].[N:2]12[CH2:11][CH:6]3[CH2:7][CH:8]([CH2:10][CH:4]([C@H:5]3[NH2:12])[CH2:3]1)[CH2:9]2.[S:13]1[C:17]([C:18](O)=[O:19])=[CH:16][C:15]2[S:21][CH:22]=[CH:23][C:14]1=2.N>>[ClH:1].[N:2]12[CH2:11][CH:6]3[CH2:7][CH:8]([CH2:10][CH:4]([C@H:5]3[NH:12][C:18]([C:17]3[S:13][C:14]4[CH:23]=[CH:22][S:21][C:15]=4[CH:16]=3)=[O:19])[CH2:3]1)[CH2:9]2

참가 물질

4

반응물 3

HCID 222AmmoniaHCID 660319Thieno(3,2-b)thiophene-2-carboxylic acidHCID 671521221-Azatricyclo[3.3.1.1,3,7]decan-4-amine hydrochloride

생성물 1

HCID 67152204HCID 67152204, 화합물

실험 절차

Prepared from (4r)-1-azatricyclo[3.3.1.13,7]dec-4-ylamine hydrochloride and thieno[3,2-b]thiophene-2-carboxylic acid according to methods A and C. 1H NMR (300 MHz, methanol-d4) δ ppm 2.08-2.34 (m, 5H), 2.51 (s, 2H), 3.42-3.64 (m, 4H), 3.88 (d, J=12.5 Hz, 2H), 4.33 (s, 1H), 7.37 (d, J=5.1 Hz, 1H), 7.71 (d, J=5.1 Hz, 1H), 8.12 (s, 1H). MS (DCI/NH3) m/z 319.

출처 및 근거

ORD 기록
ord-fd28e186a03c43b1bf12f849dee230a4
출처 데이터셋
uspto-grants-2011_03
특허 번호
US07897766B2

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