Diethyl Ether → (S)-2-phenylpropionic acid hydrazide monohydrochloride
반응식
C(OCC)(=O)C.[ClH:7].[C:8]1([C@H:14]([CH3:26])[C:15]([NH:17][NH:18]C(OC(C)(C)C)=O)=[O:16])[CH:13]=[CH:12][CH:11]=[CH:10][CH:9]=1.C(OCC)C>C(OCC)(=O)C>[ClH:7].[C:8]1([C@H:14]([CH3:26])[C:15]([NH:17][NH2:18])=[O:16])[CH:13]=[CH:12][CH:11]=[CH:10][CH:9]=1참가 물질
5
실험 절차
4 N hydrogen chloride-ethyl acetate (2 mL) was added to a suspension of tert-butyl N′-((S)-2-phenylpropionyl)hydrazinecarboxylate (470 mg) in ethyl acetate (4 mL), and the reaction solution was stirred at room temperature overnight. Diethyl ether (6 mL) was added to the reaction solution, and the precipitated powder was collected by filtration. The resulting solid was dried under reduced pressure to obtain 280 mg of the title compound. The property values of the compound are as follows.
후처리
- filtrationthe precipitated powder was collected by filtration
- customThe resulting solid was dried under reduced pressure
출처 및 근거
- ORD 기록
- ord-41e40c4ab0304f899b4160be07393244
- 출처 데이터셋
- uspto-grants-2011_03
- 특허 번호
- US07897632B2
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