3-Pyridinemethanamine → 4-((Pyridin-3-ylmethyl)amino)benzo[d][1,2,3]triazine-8-carboxamide

HRID 59962노트

반응식

HRID 59962 반응식
[N:1]1[CH:6]=[CH:5][CH:4]=[C:3]([CH2:7][NH2:8])[CH:2]=1.O[C:10]1[C:11]2[CH:19]=[CH:18][CH:17]=[C:16]([C:20]([NH2:22])=[O:21])[C:12]=2[N:13]=[N:14][N:15]=1>>[N:1]1[CH:6]=[CH:5][CH:4]=[C:3]([CH2:7][NH:8][C:10]2[C:11]3[CH:19]=[CH:18][CH:17]=[C:16]([C:20]([NH2:22])=[O:21])[C:12]=3[N:13]=[N:14][N:15]=2)[CH:2]=1

참가 물질

3

반응물 2

HCID 310183-PyridinemethanamineHCID 1785136134-oxo-1H-1,2,3-benzotriazine-8-carboxamide

생성물 1

HCID 760735744-((Pyridin-3-ylmethyl)amino)benzo[d][1,2,3]triazine-8-carboxamide

실험 절차

Compound 3 was prepared following general synthetic scheme 7 wherein pyridin-3-ylmethanamine was reacted with 4-hydroxybenzo[d][1,2,3]-triazine-8-carboxamide to give the title compound. LC-MS [281 (M+1)], 1H NMR (400 MHz, DMSO-d): δ 9.38-9.32 (m, 2H), 8.66 (s, 1H), 8.54 (d, 1H), 8.50-8.48 (m, 2H), 8.05 (s, 1H), 7.99 (t, 1H), 7.82 (d, 1H), 7.38-7.35 (m, 1H), 4.93 (s, 2H).

후처리

  1. customCompound 3 was prepared

출처 및 근거

ORD 기록
ord-520fcceac82745849943375f9974fd78
출처 데이터셋
uspto-grants-2016_09
특허 번호
US09440968B2

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