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Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
HRID 59966생성일: 2026년 10월 25일

[5-(Trifluoromethyl)pyridin-2-yl]methanamine → 4-(((5-(Trifluoromethyl)pyridin-2-yl)methyl)amino)benzo[d][1,2,3]triazine-8-carboxamide

https://huagongshe.com/reaction/59966

반응식

참여 물질

역할이름HCID투입량
반응물[5-(Trifluoromethyl)pyridin-2-yl]methanamineHCID 3796375—
반응물4-oxo-1H-1,2,3-benzotriazine-8-carboxamideHCID 178513613—
생성물4-(((5-(Trifluoromethyl)pyridin-2-yl)methyl)amino)benzo[d][1,2,3]triazine-8-carboxamideHCID 76073578—

반응 단계

Compound 7 was prepared following general synthetic scheme 7 wherein (5-(trifluoromethyl)-pyridin-2-yl)methanamine was reacted with 4-hydroxybenzo[d][1,2,3]-triazine-8-carboxamide to give the title compound. LC-MS [349 (M+1)], 1H NMR (400 MHz, DMSO-d): δ 9.50 (t, 1H), 9.35 (s, 1H), 8.93 (s, 1H), 8.55 (d, 2H), 8.16 (dd, 1H), 8.05-8.01 (m, 2H), 7.65 (d, 1H), 5.07 (d, 2H).

출처 및 근거

DOI10.6084/m9.figshare.5104873.v1
특허 번호US09440968B2
출처 데이터셋uspto-grants-2016_09
ORD IDord-143ee002a12e4c7091af4fc0d04bc553
출처 메모uspto-grants-2016_09