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Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
HRID 600251생성일: 2026년 10월 26일

(R)-(-)-1-(2-Pyrrolidinylmethyl)pyrrolidine → [6-(4-Methyl-piperazin-1-yl)-5,6,7,8-tetrahydro-naphthalen-2-yl]-(2-pyrrolidin-1-ylmethyl-pyrrolidin-1-yl)-methanone

https://huagongshe.com/reaction/600251

반응식

참여 물질

역할이름HCID투입량
반응물(R)-(-)-1-(2-Pyrrolidinylmethyl)pyrrolidineHCID 853151—
반응물6-(4-Methyl-piperazin-1-yl)-5,6,7,8-tetrahydro-naphthalene-2-carboxylic acid dihydrochlorideHCID 67272971—
생성물[6-(4-Methyl-piperazin-1-yl)-5,6,7,8-tetrahydro-naphthalen-2-yl]-(2-pyrrolidin-1-ylmethyl-pyrrolidin-1-yl)-methanoneHCID 67273459—

반응 단계

[6-(4-methyl-piperazin-1-yl)-5,6,7,8-tetrahydro-naphthalen-2-yl]-(2-pyrrolidin-1-ylmethyl-pyrrolidin-1-yl)-methanone is prepared from 6-(4-methyl-piperazin-1-yl)-5,6,7,8-tetrahydro-naphthalene-2-carboxylic acid dihydrochloride and (R)-(+)-1-(2-pyrrolidinylmethyl)-pyrrolidine in a manner substantially analogous to Procedure C (See herein Example 13). Observed mass 411 (M++1).

출처 및 근거

DOI10.6084/m9.figshare.5104873.v1
특허 번호US07902191B2
출처 데이터셋uspto-grants-2011_03
ORD IDord-31d1d47127ad4b4b8ce2e652ceb3582b
출처 메모uspto-grants-2011_03