Trifluoroacetohydrazide → HCID 178446280, 화합물

HRID 600593노트

반응식

HRID 600593 반응식
[CH2:1]([NH:6][C:7]1[N:8]=[CH:9][NH:10][C:11]=1[C:12](SC)=[NH:13])[CH2:2][CH2:3][CH2:4][CH3:5].[F:16][C:17]([F:23])([F:22])[C:18]([NH:20][NH2:21])=O>C(O)C>[CH2:1]([NH:6][C:7]1[N:8]=[CH:9][NH:10][C:11]=1[C:12]1[NH:21][N:20]=[C:18]([C:17]([F:23])([F:22])[F:16])[N:13]=1)[CH2:2][CH2:3][CH2:4][CH3:5]

참가 물질

4

반응물 2

HCID 229753TrifluoroacetohydrazideHCID 135984704methyl 4-(pentylamino)-1H-imidazole-5-carbimidothioate

생성물 1

HCID 178446280HCID 178446280, 화합물

시약·촉매·용매 1

HCID 702Ethanol용매

실험 절차

The mixture of methyl 4-(pentylamino)-1H-imidazole-5-carbimidothioate (0.53 g, 2.4 mmol) and trifluoroacetic acid hydrazide (0.45 g, 3.5 mmol) in ethanol (10 mL) was refluxed overnight. The reaction mixture was concentrated to yield the product as slightly green viscous oil. LCMS calculated for C11H16F3N6(M+H): 289.1. found: 289.1.

후처리

  1. temperaturewas refluxed overnight
  2. concentrationThe reaction mixture was concentrated
  3. customto yield the product as slightly green viscous oil

출처 및 근거

ORD 기록
ord-8bd79e5af0ec49d2a526a811eb6afa3b
출처 데이터셋
uspto-grants-2011_03
특허 번호
US07902205B2

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