Trifluoroacetic acid → HCID 178448706, 화합물
반응식
[CH2:1]([N:5]1[C:13]2[N:12](C3CCCCO3)[CH:11]=[N:10][C:9]=2[C:8]2=[N:20][N:21]=[CH:22][N:7]2[C:6]1=[O:23])[CH:2]([CH3:4])[CH3:3].C(O)(C(F)(F)F)=O>C(Cl)Cl>[CH2:1]([N:5]1[C:13]2[NH:12][CH:11]=[N:10][C:9]=2[C:8]2=[N:20][N:21]=[CH:22][N:7]2[C:6]1=[O:23])[CH:2]([CH3:4])[CH3:3]참가 물질
4
실험 절차
To a solution of 6-isobutyl-7-(tetrahydro-2H-pyran-2-yl)-6,7-dihydro-5H-[1,2,4]triazolo[3,4-i]purin-5-one (20 mg, 0.06 mmol) in methylene chloride (0.8 mL) was added TFA (0.1 mL, 1 mmol) dropwise. After stirring at room temperature for 30 minutes, the reaction mixture was concentrated to give the crude product which was used for next step without further purification. LCMS calculated for C10H13N6O (M+H): 233.1. found: 233.1.
후처리
- concentrationthe reaction mixture was concentrated
출처 및 근거
- ORD 기록
- ord-e0836ca234be4424abc94c7d53dbd077
- 출처 데이터셋
- uspto-grants-2011_03
- 특허 번호
- US07902205B2
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