Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
5-Quinolinamine, 2-methyl- → 3-(1-Ethyl-1,2,3,4-tetrahydro-1-naphthalenyl)-1,1,1-trifluoro-2-[[(2-methyl-5-quinolinyl) amino]methyl]-2-propanol
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 5-Quinolinamine, 2-methyl- | HCID 148683 | — |
| 반응물 | 2-[(1-Ethyl-1,2,3,4-tetrahydro-1-naphthalenyl)methyl]-2-(trifluoromethyl)oxirane | HCID 11630585 | — |
| 생성물 | 3-(1-Ethyl-1,2,3,4-tetrahydro-1-naphthalenyl)-1,1,1-trifluoro-2-[[(2-methyl-5-quinolinyl) amino]methyl]-2-propanol | HCID 11568433 | — |
반응 단계
Similar reaction of 2-[(1-ethyl-1,2,3,4-tetrahydro-1-naphthalenyl)methyl]-2-(trifluoromethyl)oxirane (D2, racemic diastereomer 2) (Intermediate 15) with 2-methyl-5-quinolinamine afforded Example 5-D2 (racemic diastereomer 2).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07902224B2 |
| 출처 데이터셋 | uspto-grants-2011_03 |
| ORD ID | ord-eb3788e442fe4939a2b42801005995fa |
| 출처 메모 | uspto-grants-2011_03 |