p-(Dimethoxymethyl)anisole → HCID 57667078, 화합물

HRID 600847

반응식

HRID 600847 반응식
[C:1]([O:5][C:6]([N:8]1[C@@:12](C(C)(C)C)([CH2:13][NH:14][C:15]2[CH:20]=[CH:19][CH:18]=[C:17]([Cl:21])[CH:16]=2)[CH2:11][O:10][C:9]1([CH3:27])[CH3:26])=[O:7])([CH3:4])([CH3:3])[CH3:2].CO[CH:30](OC)[C:31]1[CH:36]=[CH:35][C:34]([O:37][CH3:38])=[CH:33][CH:32]=1>>[C:1]([O:5][C:6]([N:8]1[C@@H:12]([CH2:13][N:14]([C:15]2[CH:20]=[CH:19][CH:18]=[C:17]([Cl:21])[CH:16]=2)[CH2:30][C:31]2[CH:36]=[CH:35][C:34]([O:37][CH3:38])=[CH:33][CH:32]=2)[CH2:11][O:10][C:9]1([CH3:27])[CH3:26])=[O:7])([CH3:3])([CH3:4])[CH3:2]

참가 물질

3

반응물 2

HCID 75140p-(Dimethoxymethyl)anisoleHCID 67271544HCID 67271544, 화합물

생성물 1

HCID 57667078HCID 57667078, 화합물

실험 절차

In analogy to example 20.a tert-butyl (S)-4-[(3-chloro-phenylamino)-methyl]-2,2-dimethyl-oxazolidine-3-carboxylic acid tert-butyl ester was reacted with p-anisaldehyde dimethyl acetal to give (S)-4-{[(3-chloro-phenyl)-(4-methoxy-benzyl)-amino]-methyl}-2,2-dimethyl-oxazolidine-3-carboxylic acid tert-butyl ester. White solid. MS (ISP): 463.1 ([{37Cl}M+H]+), 461.1 ([{35Cl}M+H]+)

출처 및 근거

ORD 기록
ord-005aacae5fd344de8f4f18bd1ae3daf7
출처 데이터셋
uspto-grants-2011_03
특허 번호
US07902238B2

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