Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Toluene → Methyl 3-amino-3-methylbutanoate
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Toluene | HCID 1140 | — |
| 반응물 | Thionyl Chloride | HCID 24386 | — |
| 반응물 | 3-Amino-3-methylbutanoic acid | HCID 2760933 | — |
| 용매 | Methanol | HCID 887 | — |
| 생성물 | Methyl 3-amino-3-methylbutanoate | HCID 18667677 | — |
반응 단계
To 3-amino-3-methyl-butyric acid 10-1 (1 eq.) in methanol at 0° C. was added 2 eq. of thionyl chloride. The reaction mixture was warmed to room temperature and stirred overnight. The solvent was evaporated to give azeotropic mixture of 10-2 and toluene (x=3) which was used for Step B. MS: MH+=132.1
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07902240B2 |
| 출처 데이터셋 | uspto-grants-2011_03 |
| ORD ID | ord-bb6106fff1594252865d9d33fdecda9a |
| 출처 메모 | uspto-grants-2011_03 |