Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
2-Amino-5-bromobenzenesulfonamide → N-[2-(aminosulfonyl)phenyl]-4-hydroxy-1-isobutoxy-2-oxo-1,2-dihydro-1,8-naphthyridine-3-carboxamide
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 2-Amino-5-bromobenzenesulfonamide | HCID 820700 | — |
| 반응물 | Ethyl 1-benzyl-4-hydroxy-2-oxo-1,2-dihydro-1,8-naphthyridine-3-carboxylate | HCID 54729304 | — |
| 반응물 | Ethyl 4-hydroxy-1-isobutoxy-2-oxo-1,2-dihydro-1,8-naphthyridine-3-carboxylate | HCID 67063850 | — |
| 생성물 | N-[2-(aminosulfonyl)phenyl]-4-hydroxy-1-isobutoxy-2-oxo-1,2-dihydro-1,8-naphthyridine-3-carboxamide | HCID 67063721 | — |
반응 단계
The title compound was prepared according to the procedure of Example 84C substituting the product of Example 158C for the product of Example 84B and substituting 2-aminosulfonamide for the product of Example 84A (0.225 g, 86%). MS (DCI) m/z 433 (M+H)+.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07902203B2 |
| 출처 데이터셋 | uspto-grants-2011_03 |
| ORD ID | ord-1629f0fa9137457498f312b150ff84fd |
| 출처 메모 | uspto-grants-2011_03 |