2-Amino-5-bromobenzenesulfonamide → N-[2-(aminosulfonyl)-5-chlorothien-3-yl]-1-benzyl-4-hydroxy-2-oxo-1,2-dihydroquinoline-3-carboxamide

HRID 601169

반응식

HRID 601169 반응식
[NH2:1][C:2]1[CH:6]=[C:5]([Cl:7])[S:4][C:3]=1[S:8]([NH2:11])(=[O:10])=[O:9].NC1C=CC(Br)=CC=1S(N)(=O)=O.[CH2:24]([N:31]1[C:40]2[C:35](=[CH:36][CH:37]=[CH:38][CH:39]=2)[C:34]([OH:41])=[C:33]([C:42](OCC)=[O:43])[C:32]1=[O:47])[C:25]1[CH:30]=[CH:29][CH:28]=[CH:27][CH:26]=1>>[NH2:11][S:8]([C:3]1[S:4][C:5]([Cl:7])=[CH:6][C:2]=1[NH:1][C:42]([C:33]1[C:32](=[O:47])[N:31]([CH2:24][C:25]2[CH:30]=[CH:29][CH:28]=[CH:27][CH:26]=2)[C:40]2[C:35]([C:34]=1[OH:41])=[CH:36][CH:37]=[CH:38][CH:39]=2)=[O:43])(=[O:9])=[O:10]

참가 물질

4

반응물 3

HCID 8207002-Amino-5-bromobenzenesulfonamideHCID 109559343-Amino-5-chlorothiophene-2-sulfonamideHCID 54711837Ethyl 1-benzyl-4-hydroxy-2-oxo-1,2-dihydroquinoline-3-carboxylate

생성물 1

HCID 67063731N-[2-(aminosulfonyl)-5-chlorothien-3-yl]-1-benzyl-4-hydroxy-2-oxo-1,2-dihydroquinoline-3-carboxamide

실험 절차

The title compound is prepared according to the procedure of Example 84C substituting the product of Example 174A for the product of Example 84A and substituting the product of Example 99A for the product of example Example 84B.

출처 및 근거

ORD 기록
ord-28bde75c0e594c23bc7208f753ae7cbe
출처 데이터셋
uspto-grants-2011_03
특허 번호
US07902203B2

연결된 노트

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