Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Thionyl Chloride → 3,5-Dimethoxy-4-(2-propynyloxy)benzoyl chloride
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Thionyl Chloride | HCID 24386 | — |
| 반응물 | 3,5-Dimethoxy-4-[(prop-2-yn-1-yl)oxy]benzoic acid | HCID 13121481 | — |
| 촉매 | Dimethylformamide | HCID 6228 | — |
| 용매 | Toluene | HCID 1140 | — |
| 생성물 | 3,5-Dimethoxy-4-(2-propynyloxy)benzoyl chloride | HCID 57445669 | 85.6% |
반응 단계
To 100 ml of toluene were added 13.0 g of 4-(2-propynyloxy)-3,5-dimethoxybenzoic acid, 9.5 g of thionyl chloride and 50 mg of DMF and the mixture obtained was heated under reflux for 3 hours. Then, the reaction mixture was concentrated. The solid obtained was washed with hexane to obtain 12.0 g of 4-(2-propynyloxy)-3,5-dimethoxybenzoyl chloride represented by the formula:
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07902400B2 |
| 출처 데이터셋 | uspto-grants-2011_03 |
| ORD ID | ord-f63dacc09c7d4a4f95a8a975ee2a7d75 |
| 출처 메모 | uspto-grants-2011_03 |