Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Thionyl Chloride → 3-Methoxy-4-(2-propynyloxy)benzoyl chloride
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Thionyl Chloride | HCID 24386 | — |
| 반응물 | 3-Methoxy-4-(prop-2-ynyloxy)benzoic acid | HCID 13121480 | — |
| 촉매 | Dimethylformamide | HCID 6228 | — |
| 용매 | Toluene | HCID 1140 | — |
| 생성물 | 3-Methoxy-4-(2-propynyloxy)benzoyl chloride | HCID 57445671 | 84.1% |
반응 단계
To 100 ml of toluene were added 12.0 g of 4-(2-propynyloxy)-3-methoxybenzoic acid, 9.0 g of thionyl chloride and 50 mg of DMF, and the mixture obtained was heated under reflux for 3 hours. Then, the reaction mixture was concentrated. The solid obtained was washed with hexane to obtain 11.0 g of 4-(2-propynyloxy)-3-methoxybenzoyl chloride represented by the formula.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07902400B2 |
| 출처 데이터셋 | uspto-grants-2011_03 |
| ORD ID | ord-c4844b0198954552a6ae17f7c6d001e8 |
| 출처 메모 | uspto-grants-2011_03 |