Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
1-(Pyridazin-3-yl)piperidin-4-amine → 6-(3-fluorophenyl)-N-(1-pyridazin-3-ylpiperidin-4-yl)nicotinamide
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 1-(Pyridazin-3-yl)piperidin-4-amine | HCID 62482004 | — |
| 반응물 | N-(1-{5-[(2,5-dimethyl-2,5-dihydro-1H-pyrrol-1-yl)carbonyl]pyridin-2-yl}piperidin-4-yl)-6-(3-fluorophenyl)nicotinamide | HCID 67267283 | — |
| 생성물 | 6-(3-fluorophenyl)-N-(1-pyridazin-3-ylpiperidin-4-yl)nicotinamide | HCID 59743937 | — |
반응 단계
6-(3-fluorophenyl)-N-(1-pyridazin-3-ylpiperidin-4-yl)nicotinamide was prepared analogous to N-(1-{5-[(2,5-dimethyl-2,5-dihydro-1H-pyrrol-1-yl)carbonyl]pyridin-2-yl}piperidin-4-yl)-6-(3-fluorophenyl)nicotinamide, except 1-(pyridazin-3-yl)piperidin-4-amine was used as R—NH2. M+H=378.3 observed, 378.17 expected.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07902373B2 |
| 출처 데이터셋 | uspto-grants-2011_03 |
| ORD ID | ord-0e4212f700554afa853a4788c06354d7 |
| 출처 메모 | uspto-grants-2011_03 |