Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
1-Boc-3-hydroxypiperidine → 1-(tert-Butoxycarbonyl)-3-[[2-(4-chlorophenyl)-4-methylthiazol-5-yl]methoxy]piperidine
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 1-Boc-3-hydroxypiperidine | HCID 545699 | — |
| 반응물 | 5-(Chloromethyl)-2-(4-chlorophenyl)-4-methyl-1,3-thiazole | HCID 2763694 | — |
| 생성물 | 1-(tert-Butoxycarbonyl)-3-[[2-(4-chlorophenyl)-4-methylthiazol-5-yl]methoxy]piperidine | HCID 57572140 | 44.2% |
반응 단계
Using 1-(tert-butoxycarbonyl)-3-hydroxypiperidine (201 mg, 1.00 mmol) and 5-chloromethyl-2-(4-chlorophenyl)-4-methylthiazole (258 mg, 1.00 mmol), the same procedure was followed as in Step 5a of Example 5 to give 187 mg (44%) of the desired compound as a colorless oil.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07902367B2 |
| 출처 데이터셋 | uspto-grants-2011_03 |
| ORD ID | ord-6fcabbb6b52b4193a2399ef056a7b722 |
| 출처 메모 | uspto-grants-2011_03 |