3-[(4'-Chlorobiphenyl-4-yl)methoxy]piperidine → HCID 58992599, 화합물

반응식

[Cl:1][C:2]1[CH:7]=[CH:6][C:5]([C:8]2[CH:13]=[CH:12][C:11]([CH2:14][O:15][CH:16]3[CH2:21][CH2:20][CH2:19][NH:18][CH2:17]3)=[CH:10][CH:9]=2)=[CH:4][CH:3]=1.[CH3:22][O:23][C:24]([C:26]1[CH:27]=[C:28](OB(O)O)[CH:29]=[CH:30][CH:31]=1)=[O:25]>>[Cl:1][C:2]1[CH:7]=[CH:6][C:5]([C:8]2[CH:13]=[CH:12][C:11]([CH2:14][O:15][CH:16]3[CH2:21][CH2:20][CH2:19][N:18]([C:30]4[CH:31]=[C:26]([CH:27]=[CH:28][CH:29]=4)[C:24]([O:23][CH3:22])=[O:25])[CH2:17]3)=[CH:10][CH:9]=2)=[CH:4][CH:3]=1

참가 물질

반응물 2

HCID 589926553-[(4'-Chlorobiphenyl-4-yl)methoxy]piperidine

HCID 671702873-Methoxycarbonylphenylboric acid

생성물 1

HCID 58992599HCID 58992599, 화합물수율 34%

실험 절차

Using 3-[(4′-chlorobiphenyl-4-yl)methoxy]piperidine (220 mg, 0.729 mmol) and 3-(methoxycarbonyl)phenylboric acid (263 mg, 1.46 mmol), the same procedure was followed as in Example 2 to give 107 mg (34%) of the desired compound as a colorless oil.

출처 및 근거

ORD 기록: ord-f8f6b2cdb55a4d9f960defef0c7057e3
출처 데이터셋: uspto-grants-2011_03
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US07902367B2

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