Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Morpholine → Morpholine-4-carboxamide
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Morpholine | HCID 8083 | — |
| 반응물 | Trimethylsilyl isocyanate | HCID 70696 | — |
| 용매 | Isopropanol | HCID 3776 | — |
| 생성물 | Morpholine-4-carboxamide | HCID 75088 | 102.4% |
반응 단계
To a stirred solution of morpholine (1.3 mL, 15 mmol) in isopropanol (30 mL) at rt was added trimethylsilylisocyanate (2.8 mL, 21 mmol) and the resulting solution stirred overnight before the volatiles were removed in vacuo to give morpholine-4-carboxylic acid amide (2.0 g, quant.) as a solid; 1H-NMR (300 MHz, d6-DMSO) 6.00 (2H, s), 3.51-3.54 (4H, s), 3.23-3.26 (4H, s).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07906533B2 |
| 출처 데이터셋 | uspto-grants-2011_03 |
| ORD ID | ord-72b796d8e7204dd599c7a71d3fddf1fd |
| 출처 메모 | uspto-grants-2011_03 |