Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
2-(tert-Butylamino)ethanol → 1-(Benzyloxy)-3-(tert-butyl(2-hydroxyethyl)amino)propan-2-ol
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 2-(tert-Butylamino)ethanol | HCID 78361 | — |
| 반응물 | Benzyl glycidyl ether | HCID 94247 | — |
| 용매 | Ethanol | HCID 702 | — |
| 생성물 | 1-(Benzyloxy)-3-(tert-butyl(2-hydroxyethyl)amino)propan-2-ol | HCID 57656862 | 83.5% |
반응 단계
A solution of 2-[(benzyloxy)methyl]oxirane (350 mg) and 2-(tert-butylamino)ethanol (500 mg) in ethanol (20 mL) was heated to reflux temperature and left at this temperature overnight. The solution was concentrated at reduced pressure. The residue was purified by filtration through a short pad of silica eluting with 20% methanol in dichloromethane. This gave the title compound as a colourless oil (501 mg)
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07906645B2 |
| 출처 데이터셋 | uspto-grants-2011_03 |
| ORD ID | ord-006fedb16250481cbc8dc74c7ccb5e7b |
| 출처 메모 | uspto-grants-2011_03 |