4-(4-tert-butylphenyl)butanoic Acid → HCID 66672660, 화합물

HRID 604535노트

반응식

HRID 604535 반응식
[C:1]([O:4][CH2:5][C@@:6]([NH:40][C:41](=[O:43])[CH3:42])([CH3:39])[CH2:7][CH2:8][C:9]1[N:10]([CH3:38])[C:11](C(OC(=O)CCCC2C=CC(C)=CC=2)=CCCC2C=CC(C)=CC=2)=[CH:12][CH:13]=1)(=[O:3])[CH3:2].C(C1C=CC(CCCC(O)=O)=CC=1)(C)(C)C>>[C:1]([O:4][CH2:5][C@@:6]([NH:40][C:41](=[O:43])[CH3:42])([CH3:39])[CH2:7][CH2:8][C:9]1[N:10]([CH3:38])[CH:11]=[CH:12][CH:13]=1)(=[O:3])[CH3:2]

참가 물질

3

반응물 2

HCID 50189424-(4-tert-butylphenyl)butanoic AcidHCID 67040558HCID 67040558, 화합물

생성물 1

HCID 66672660HCID 66672660, 화합물

실험 절차

The reaction was carried out in the similar manner to (1a) using 4-(4-t-butylphenyl)butyric acid obtained in Reference example 7 and (2R)-1-acetoxy-2-acetylamino-2-methyl-4-(1-methylpyrrol-2-yl)butane obtained in Reference example 1 to obtain the title compound (yield: 59%).

출처 및 근거

ORD 기록
ord-e77ce376be954fef96c54e8bd050857d
출처 데이터셋
uspto-grants-2011_03
특허 번호
US07910617B2

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