HCID 66672660, 화합물 → HCID 67040053, 화합물

HRID 604555노트

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HRID 604555 반응식
[C:1]([O:4][CH2:5][C@@:6]([NH:16][C:17](=[O:19])[CH3:18])([CH3:15])[CH2:7][CH2:8][C:9]1[N:10]([CH3:14])[CH:11]=[CH:12][CH:13]=1)(=[O:3])[CH3:2].[CH2:20]([C@@]1(CCC2N(C)C=CC=2)COC(=O)N1)C>>[C:1]([O:4][CH2:5][C@@:6]([NH:16][C:17](=[O:19])[CH3:18])([CH2:15][CH3:20])[CH2:7][CH2:8][C:9]1[N:10]([CH3:14])[CH:11]=[CH:12][CH:13]=1)(=[O:3])[CH3:2]

참가 물질

3

반응물 2

HCID 66672660HCID 66672660, 화합물HCID 67040210(4R)-4-Ethyl-4-[2-(1-methyl-1H-pyrrol-2-yl)ethyl]-1,3-oxazolidin-2-one

생성물 1

HCID 67040053HCID 67040053, 화합물수율 77%

실험 절차

The reaction was carried out in the similar manner to Reference example 1 (1 g) and (1h) using (4R)-4-ethyl-4-[2-(1-methylpyrrol-2-yl)ethyl]-1,3-oxazolidin-2-one obtained Reference example 2 (2e) as a starting material to obtain the title compound (yield: 77%).

출처 및 근거

ORD 기록
ord-77d0eb21ae2f490f8e42593d08ad2b8d
출처 데이터셋
uspto-grants-2011_03
특허 번호
US07910617B2

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